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They include both people who didn't respond to the drug, because not everyone is going to benefit from the drug, and "high responders." The high responders reported six to eight more satisfying sexual events each month, and a return of their sexual desire score to what's considered normal. Nevertheless, the effect of a medication may not be needed beyond 6 or 8 hours, and any side effects (in addition to any positive effect) they cause will fade rapidly as the medication leaves the bloodstream. Respondents referred to the necessary criteria, which should be met by ED therapy, "action every time" (66.1%), "rapid onset of effect" (63.2%) and "convenience of reception" (61.3%)

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Priapism is the name for a painful erection lasting for longer than 4 hours.

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